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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKG1
All Species:
19.7
Human Site:
Y242
Identified Species:
61.9
UniProt:
Q13976
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13976
NP_001091982.1
671
76364
Y242
D
V
L
E
E
T
H
Y
E
N
G
E
Y
I
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851997
510
57367
G124
P
V
F
L
R
T
L
G
K
G
D
W
F
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P0C605
671
76332
Y242
D
V
L
E
E
T
H
Y
E
N
G
E
Y
I
I
Rat
Rattus norvegicus
Q64595
762
87163
Y307
D
C
L
E
V
E
Y
Y
D
K
G
D
Y
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03043
1088
121322
Y659
D
V
L
E
E
T
H
Y
Q
R
G
D
Y
I
V
Honey Bee
Apis mellifera
NP_001011581
678
77281
Y241
D
V
L
E
E
T
F
Y
N
N
G
D
Y
I
I
Nematode Worm
Caenorhab. elegans
O76360
780
86723
Y340
D
V
M
D
Q
D
Y
Y
D
G
G
H
Y
I
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
68.6
N.A.
99.5
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.9
61.2
45.1
N.A.
Protein Similarity:
100
N.A.
N.A.
72.2
N.A.
99.8
65.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
75.9
61.6
N.A.
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
100
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
80
46.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
26.6
N.A.
100
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
93.3
86.6
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
0
13
0
13
0
0
25
0
13
38
0
0
0
% D
% Glu:
0
0
0
63
50
13
0
0
25
0
0
25
0
0
13
% E
% Phe:
0
0
13
0
0
0
13
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
0
25
75
0
0
13
0
% G
% His:
0
0
0
0
0
0
38
0
0
0
0
13
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
63
% I
% Lys:
0
0
0
0
0
0
0
0
13
13
0
0
0
0
0
% K
% Leu:
0
0
63
13
0
0
13
0
0
0
0
0
0
0
0
% L
% Met:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
38
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
13
0
0
0
0
13
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
63
0
0
0
0
0
0
0
0
0
% T
% Val:
0
75
0
0
13
0
0
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% W
% Tyr:
0
0
0
0
0
0
25
75
0
0
0
0
75
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _